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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0a0b7d7a14dd97e9c86cffb056fc11e639716bdf5fd021c21aec5682c1ba1a0a' 
  AND token = 'HvDdfBX2S0MSNi4R0oQayIdar6hItJ/GeoM7ExOCzyM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}