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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6b38b4836a8b2aa5c3858b04901884d40e725e7d5cfc105806ce243206d41d0a' 
  AND token = 'yIA35kqyZa4gFk8F+BmM3CrlWRYjRkJ39bOC5+q5jbA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00050

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}