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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '22f1a4b948ad401ae407da4409d733d40d973eea80f28cdbde51c1b96a7c44b0' 
  AND token = 'hDkUs0+KCsfOhe29J+GWEzoWk516MQOEQBhBrL2eQNg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}