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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6cf3fe108b84fc1b083433aec4f4e9c1480968bd5cee23f44c8800965ad50609' 
  AND token = 'mtE87FKTnTI7aBUzwlk/LVoHKLVCMT2/cH6JYX57uwU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}