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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2f95c1c7ca27cd7ce2c162eb3db5314642f80f0871d9357387b53f52da2387b1' 
  AND token = '4td2WNP1xxdz6diw/1vKHLuTtxsOq7Wjqu/alD1r5oA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00051

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}