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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e5e661d8a7adcecd2927781ca5512ec9217297fcc5a0f1fc289124b01e913af8' 
  AND token = 'NrV6bQhEvLQjrzYhNmA++0Pw/mQ+WQU0y+iqF3TmJSI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}