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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '21ab74fe8036ec5b7cb8ea84867e2f3a1c451e39570fbb5a95a4716611ca28d6' 
  AND token = 'pIaA2+yl92k1zCM3FtIdIRi98vTetsXVRyRzXH8EAb4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}