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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '08d0e792344d6cc1dc010275ec3c66d028f1c01486440e48c927e2d35790982c' 
  AND token = 'RDs+LMQ3g3DoHyeOSBj+aZPyjAbpLDh9rggUXm5cxj0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}