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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4a0ccb74fa1c331874e2fa0a4a8b9db5844f5dac469c5af8be92115297fb7e4c' 
  AND token = 't+IcOivNHRqr4pU4JUR6JHmNE8im5qL3AVH/wJ/uMjc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}