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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3f0d2a2dee2f84925db88feec9b8306686e9b08fd352a256443e9c35e4a994d0' 
  AND token = 'KuA3w3wNLJB/jA40j6xy0SCl01xLpI1C9ZbQl/9E9TM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}