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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b4e016e07d6c51ff5521666ec8b801e2a1a74096c9a71d57767c4d9da484ab71' 
  AND token = 'ub6PrH3DtmPkIUdOyP1wLWOxdiAE+dOE0TN0dBF4j7I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00057

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}