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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ad3a5bb4c60a325350f0fa15a2be100c058befd10d44f1f16f2285976a4f4599' 
  AND token = 'RaopQ2AArVos5CS4W02Wi4xiJYwD0qPQhnYQKQfBdsA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00051

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}