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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5b4db75463d0ecc91d6ab083b461d8ac412f770be32ac98e6fa2026b3545362b' 
  AND token = 'uIsXE1nsCorK++9vFMiAnBX5EGZMh+GSpLOo20NzCLA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00055

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}