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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '503a4422f5d6735d450b4f904869c1b207440a02ede286e6689cb3a2e74af4d5' 
  AND token = 'KSasNWHTKZwD3UHLCW64q6eSZUuyFbcCVBk34gEacO0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}