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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8245b1c4cd89f7c64b39cd056481b9197974de74133f91e4aa0907fd9be99309' 
  AND token = 'u6mqyMBihWplxL0saw75/OZY3tms5KV1ssANu8dUag8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}