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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4b677825ef312f442673921c975d3e475e9d6700f459f87e8902207e6277fb3c' 
  AND token = '3Y4VUP3ekZ0SEnX4f3+We7q3YI6eYtjLy0i9/51vc2I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}