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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '10255776df91a764cb23e0038d8b61b79daa662e6d5cce30c4ce8349b07eb9aa' 
  AND token = 'gdgY8DfChUf/bYfmqiVNWs0fz0M3mqG1wNejRu4y0Xo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}