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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '275b1da71a18a9f24e26ffe0e9baf1e55933b743dafd3e38ebaa1e3fb803658b' 
  AND token = 'OYEkD+RUuNKxbjDdLppaYWMSN2q+CEx8EPemN6frHMg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}