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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '271bf7b2979d4af6b6dea53fb4396fcb243e8c2bcca828c399e75d9e10873e26' 
  AND token = 'BKvKOPFt+DIy1755g/MvpecLeFtneftMP/UcvyGh8SM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00051

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}