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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '38e5f080638811c51a76e076df09355628c43bb2f2872ee5d7d251f0b2fbc510' 
  AND token = 'umL8Kya89HxvjrtTVsiOHMJPRsj5HAn6BjrtRkVhZnw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00048

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}