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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '22b07e39176559c5633c305ff2b4fca5f00213c500ef95580e4868b87a48dee2' 
  AND token = 'T+yV6Q+5ci1SE9gxEjyZGoBH/qL0OUh0LATJScEdHuc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}