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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '72a856422178d6b30dcc98f8df97555d5ad6cf3d3bcc8ab57d8d64618f6102e0' 
  AND token = 'wzR5X9ryZh/f1DERN8BT38f49PYaoiqXieH3+2yy4SE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00061

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}