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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1d3ff78a4cfc77b7b8de3b6318b3c8665675fcbec4cca292298b1a21ba52c04c' 
  AND token = 'VFcv2KwC+jhDyJTMUfGGGyZbqSG20Vt4Gf1ApPn75eI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}