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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0fd6054d9b3f8235808ed7eb471e2d2fc7c5d6504f8631f55c3967b573422419' 
  AND token = '6u/ki0gd6g8Kh4ln7+ScqVKmV10V55kT4bP7f503nvA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}