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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f59e7de22056bbc6497e0c56e7197be6b94b3f1123b23bf117f75d9ae79ae7b6' 
  AND token = '8L7O1SvUcewnLF7DzkJzhiEoXqpZJRbY4vZUpdDgoz8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}