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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '27a6f206e62490498a9c8f9d399fc76e42413ddc3888f22d832bd5c363300ade' 
  AND token = 'z5UfXW4JUdU7rMqh40Eq4MY+6jSl28nmz+qpVlKKok4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}