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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ab72734f11f944e492b27436c3ccd8c736f8635130f6c4d5cae91eb85d9a68e9' 
  AND token = 'XbYZOTZwBD+rN54lDnc2rg5B2DnRIqBuhWk1IX76Y0s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00058

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}