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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1b3c9511a0153f2c21f59eda4de8989e09902d3570ac8589dba5fa29c43c1f9d' 
  AND token = 'KJJ4N1oBkFBZIp44PhnpJT8o8JW+ElZCwcfdSMVmlLc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}