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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '422184aa6949372bddf889ad26ed5177e19aed02231fe3aac0ab836374a1c2d2' 
  AND token = 'Mx+l96Q/wRKLw0pEeE0RFpnCFqTqF0ql+9yH2rUMX0c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}