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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '66f0b621e30b3c0ef837885c7cb973289d8f459352e2ff986034cb669f897122' 
  AND token = '22jJPy11LofuoDo8CYPsDHUQNH470Q4NmFf9jCh0bx8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}