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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4d38f3457727ca4d40273aef1d4a3a63f1b5d71ebd9c8cbea01c0232efd648d6' 
  AND token = 'ZJIp6SmjEvQtjGvLyUQSqHsQw76t5SO2tENLL+u5Xqo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}