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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fd573c0e81696e038f6d1b39477252bdbd136f9dab86108cf0a88bde0c4ec82c' 
  AND token = 'bO/Td6Qjq7418S9u8j7s+D7I7YvMkS0Y1w6SPZXuQPg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}