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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '36a36b8cab4aba9c946f4bb7590ab307f8f2ac7d78d50d428f119931e7b8bdc5' 
  AND token = 'WbULZHb+aM4pfpLInvfI8HOfgzRws4ASH9W93DAXZ4Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}