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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '504da75bca28f40acb5d3c817a0584230f64c6d9c88ff19930d5af5225a262c2' 
  AND token = '2k5LA/D/txZmK2hZc6Ee00ru4ahnDz8IolBjVuMDeyg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}