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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '14bfa7fd602bdc781d68361567199b9500508741446183b72f281c463bcd4b06' 
  AND token = '84EBg9jJHkSAdDut37+4/b44WwUng46/rg2TQI/4ac4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00054

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}