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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0cdbfde9ea81817db017b5177c1e13f63c4be2df4578ae13e9f7709a531f0658' 
  AND token = 'LGAIDdTVHnVFA++mUBlxGCfUXpbwDZ2cVzF9HpbiPDU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00051

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}