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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0f00a539e43e4a1c502be463c0d05317c52374a5abce0d470ad37b298389edeb' 
  AND token = 'OGSiLWkXxKw96I+3Wma7MK8syOUYO+TOKnX2B65CfrQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00061

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}