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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1448277d315ffdddbb808995d4d7a02c17b506961194cdcd839d56b3dfc4a39b' 
  AND token = 'IOW1Rz6foA0a9Z+l6b5ksVMejRfcyO3qVXIV1t9HMIs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}