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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '35fce781c7b73d725eece1a3984cde4bec75aa6f5f5b63119578d39e8a788057' 
  AND token = 'd1BAnsz5DwABg2t+u+D4ZohlQwrvdFAFGdTImWr+cpo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}