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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e4206e7555b233d8c41ea27d66c2306adbdb8e3b7eacdbddc5f192fc28d0cc51' 
  AND token = 'ZXGKj6fuAjZn9NlM9hb5nOxpFDgQdOStouMc71xp2SI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}