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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8ad9a47aecf1ae6b6d690810f71ee11de9b08db3ccd545eb7854677d6d4af224' 
  AND token = '3bmDJGZlILF6K2GZ0saWCUdMxaotga8Xrj0YDkgR4PY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}