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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6fd38e822d9db19aa11b7d399a6a560d48494bb74e03cf84240200acc1b5f41c' 
  AND token = 'ES1riVOH3x5mL2GE/nflbHrbPmRoOVrr/8ZdmjXIDCk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}