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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '74736e6d1efc62e6abc2c763e19580c90882c0c2773874379dde5468378812e1' 
  AND token = 'QWVMEDrqrPMOSnA8wXapGxd/WoPkibXI0s1/UtWgxrk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}