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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '344af447c780768ff254447dd4b533e9377ce425850f34a83172ab9fef67cbd8' 
  AND token = '39HDRemoCd1r5NCvRnYfZ5KFioxktcAXRvnfBLC5Us4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}