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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9d3581d0f58b55d1f22030b0a1bb1d96403c60b066b147d6e9d56e8d3b7265da' 
  AND token = '7sOF00kdq7scjUhIQ9Z02hfIPPl9M8nXB2Oyv5cID4I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}