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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '003a8a675a1246b4a9d0f724d0afb07a13dc3ac6ff9b3f75db142e0f8fe12746' 
  AND token = 'R7+RgadfUgCkT3+HVy1MNdpd9qAQS+79JlxLbR+iabU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00051

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}