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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '73aac51a2c48d60d6b50b0d0090266ea8f77d39a0e52ec020617389c259845bd' 
  AND token = '28QtUTM1IYJ0IG7MBJvAMIDXI3HCN3yC21XsObIDcVI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}