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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '42a01d4632d12d9dec0485518a0d9f65b7b812e7146e3e31b9abfc5cdb0a5d6c' 
  AND token = 'YpUGBc8mdHHmi9GSfbAytJ6TnMnv52uyvSEQWhNOPrM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}