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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c0818400df04bb999d7a08546bb1ea68d130581b0ba53f39d034db79a50c5ef4' 
  AND token = 'cKZSqby5d6nTiTA3i2MrkhJQPX0Cz+/Ok5EWXdyU7BI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00056

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}