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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd3c36ff3d0b74013db4cc81d95896fcab07b05aa59c44d0ebe3370c2e75c9251' 
  AND token = 'e53jk+RYfxxyAua2RsdC4D+UaVoFK4ICxki3FEAM2Vc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00072

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}